Manual all the way, as long as I get to choose the car.
I love the way I feel when I am driving one, and I feel like the car is that much cooler. However on some cars, like my '52 I want a automatic in it. Just because its fairly awkward in some of those big cars, not only in appearance but it in practicality as well, with a big bench seat across the front.
Although I have seen a couple with a dip in the center to make more room for the stick
All in all nothing is better in the world, in my mind, than a 69 boss 429 mustang.. with a 4 speed

~adam