When I did the engine swap in my 78 F100, I pulled the whole front clip off, bonnet, guards, bumper, radiator support. That made lifting and working on the engine way easy. also meant that i could attack the cancer hiding on the firewall behind the guard brackets. F100/350's are as easy to play with as meccano sets. Just a bit bigger and heavier. No need to cut nothing.
Once the gaurds are off there are only 2 bolts holding the front radiator support to the chassis.
I made up a 3 pole Teepee like gantry with a block and tackle. and rolled the truck to it , unbolted the engine, lifted the engine high enough to clear the sump and rolled the truck back. Yes I was working alone. Yes you do have to support the gearbox, bit of chain around the chassis rails and cradling underneath the bellhousing of the gearbox does the trick.
Glad its you and not me, been there done that too often.