Re: 2011 or 2012 ford f150 with the 5.0
To add on to what CatSkinner mentioned, technology in general for engine building has greatly increased primarily to using tighter machining tolerances, and better metallurgy know-how which is why some engines can get 300K+ without even thinking twice about it. Good quality oil is a definite key ingredient. Quality oil also allows you to drive farther per oil change, even more with full synthetic.
As an example, my 2000 Durango R/T, has a '360' engine, or 360cubic inch (5.9L) V8. The block itself dates back to the 70's, and was originally built to use 30W and 40W oils. The top end has been changed over the years to merely keep up in the horsepower race, but the basic engine architecture has remained the same.
I use Amsoil 5W30 full synthetic engine oil, change it once a year, and I have been using it for the last 7 years. Yes, I add oil throughout the course of the year and just recently in its 140K mile life it is starting to burn more oil than usual. I changed back to Standard oil, as it's cheaper to burn, and it still burns as much petrol based oil, as it did the higher priced synthetic, so knowingly a ring (or two) has bit the dust and I might get a few more months out of it.
In that 140K life, it's towed a 2.5 ton boat over 6K miles, various landscape, utility, and dump trailers from 0.5 to 3tons for no less than 30K miles (I own cars to commute with!). I also bought it used with 52K miles on it. It is my workhorse vehicle and the engine never once called attention to itself. I even modified it with some bolt on performance goodies and a programmer (one of the joys of computer controlled vehicles). If I didn't tow, I would be safe to assume that its 140K miles would be closer to 190K miles in regular driving, which is still rather spectacular. Who's to say the full synthetic oil I ran gave me another 5, 10, or 15K miles before my oil consumption greatly increased? Hmm. When towing on the highway the engine would turn at 2700-2900rpm in 3rd gear (1:1) and I believe the synthetic oil helped keep engine wear down. After draining it, I'd send a sample in for analysis and they said I could easily put an additional 11K on the oil without question. The oil is rated for 25K miles, or one year.
Make of that what you will :)
'00 Durango R/T 360ci 290hp (modded); 138,500m
'06 Pontiac G6 GT 3.5L 220hp; 44,000m
'12 Chrysler 200 Limited 3.6L 283hp; 13,000m
'99 Taurus 3.0L 2V Vulcan 145hp; 154,300m - Traded
Amsoil in all vehicles!