Re: 99 f250 superduty
Are you in overdrive when this happens? If so, drive at that speed in 3rd gear (rpms will be in the 2500rpm range; approx), and see if the miss still occurs. If the problem goes away, then you could rule out a fuel problem. If it's still there, it could be a number of things. A tune up can always help, especially if it's been 40K since the last one. Be sure that the plugs are gaped correctly and if the truck has original wires, replace them. Without a code it's always hard to diagnose. If it's electrical, then it'll be even harder.
'00 Durango R/T 360ci 290hp (modded); 138,500m
'06 Pontiac G6 GT 3.5L 220hp; 44,000m
'12 Chrysler 200 Limited 3.6L 283hp; 13,000m
'99 Taurus 3.0L 2V Vulcan 145hp; 154,300m - Traded
Amsoil in all vehicles!